Perioperative red blood cell infusion and deep vein thrombosis in patients with femoral and pelvic fractures: a propensity score matching

Abstract Background The relationship between perioperative red blood cell (RBC) infusion and deep vein thrombosis (DVT) has not been determined. Objectives To analyze the time-event RBC DVT in patients with femoral pelvic fractures after adjusting for confounding factors to provide reference optimizing risk factors. Methods clinical data of 569 who received surgical treatment from May 2018 December 2019 were retrospectively analyzed. Propensity score matching (PSM) was performed on 20 covariates DVT. With formation or progression as end point, analyzed by binary logistic regression. Results After 1:1 PSM included this study, 126 transfusion group non-transfusion group, respectively. Before ( P = 0.023, OR 1.496 [95% CI, 1.058-2.115]), associated fractures. This conclusion still obtained 0.038, 1.728, 95% CI (1.031, 2.896)). 2-4U > 4U is 1.833 2.667 times that ? 2U, excluding preoperative had prior infusion, 0.037, 2.231 1.049-4.745]). Conclusion Perioperative one causes fractures, positively correlated amount infusion.